The Marquette Golden Eagles versus the Iowa State Cyclones is one of 10 games on the college basketball slate on Wednesday that has a ranked team in play. We offer ATS picks for each contest in the article below.

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AP Top 25 Picks ATS Today

No. 25 UConn Huskies vs. No. 15 Baylor Bears

Spread Prediction

• Computer Prediction: Baylor 77, UConn 76
• Projected Favorite: Baylor by 1.2 points
• Pick ATS: Baylor (+3.5)

Bet on the UConn-Baylor spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 6:30 PM ET
• Location: Storrs, Connecticut
• Venue: Harry A. Gampel Pavilion
• TV Channel: Fox Sports 1
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 20 North Carolina Tar Heels vs. No. 10 Alabama Crimson Tide

Spread Prediction

• Computer Prediction: North Carolina 85, Alabama 83
• Projected Favorite: North Carolina by 2.1 points
• Pick ATS: North Carolina (-1.5)

Bet on the North Carolina-Alabama spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 7:15 PM ET
• Location: Chapel Hill, North Carolina
• Venue: Dean E. Smith Center
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 13 Florida Gators vs. Virginia Cavaliers

Spread Prediction

• Computer Prediction: Florida 76, Virginia 60
• Projected Favorite: Florida by 16.2 points
• Pick ATS: Virginia (+16.5)

Bet on the Florida-Virginia spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 7:15 PM ET
• Location: Gainesville, Florida
• Venue: Exactech Arena at the Stephen C. O’Connell Center
• TV Channel: ESPN2
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 16 Memphis Tigers vs. Louisiana Tech Bulldogs

Spread Prediction

• Computer Prediction: Memphis 85, Louisiana Tech 68
• Projected Favorite: Memphis by 16.5 points
• Pick ATS: Memphis (-10.5)

Bet on the Memphis-Louisiana Tech spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 8:00 PM ET
• Location: Memphis, Tennessee
• Venue: FedExForum
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

No. 6 Iowa State Cyclones vs. No. 5 Marquette Golden Eagles

Spread Prediction

• Computer Prediction: Iowa State 76, Marquette 74
• Projected Favorite: Iowa State by 2.1 points
• Pick ATS: Marquette (+6.5)

Bet on the Iowa State-Marquette spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 8:00 PM ET
• Location: Ames, Iowa
• Venue: James H. Hilton Coliseum
• TV Channel: ESPN+
• Live Stream: Watch this game on ESPN+

Creighton Bluejays vs. No. 1 Kansas Jayhawks

Spread Prediction

• Computer Prediction: Kansas 77, Creighton 70
• Projected Favorite: Kansas by 6.9 points
• Pick ATS: Kansas (-2.5)

Bet on the Creighton-Kansas spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 8:30 PM ET
• Location: Omaha, Nebraska
• Venue: CHI Health Center Omaha
• TV Channel: Fox Sports 1
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 9 Duke Blue Devils vs. No. 2 Auburn Tigers

Spread Prediction

• Computer Prediction: Duke 74, Auburn 73
• Projected Favorite: Duke by 1.1 points
• Pick ATS: Auburn (+1.5)

Bet on the Duke-Auburn spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 9:15 PM ET
• Location: Durham, North Carolina
• Venue: Cameron Indoor Stadium
• TV Channel: ESPN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Mississippi State Bulldogs vs. No. 18 Pittsburgh Panthers

Spread Prediction

• Computer Prediction: Pittsburgh 77, Mississippi State 76
• Projected Favorite: Pittsburgh by 1.3 points
• Pick ATS: Pittsburgh (+4.5)

Bet on the Mississippi State-Pittsburgh spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 9:15 PM ET
• Location: Starkville, Mississippi
• Venue: Humphrey Coliseum
• TV Channel: SEC Network
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

USC Trojans vs. No. 12 Oregon Ducks

Spread Prediction

• Computer Prediction: Oregon 77, USC 71
• Projected Favorite: Oregon by 5.6 points
• Pick ATS: USC (+6.5)

Bet on the USC-Oregon spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 10:30 PM ET
• Location: Los Angeles, California
• Venue: Galen Center
• TV Channel: BTN
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Fresno State Bulldogs vs. No. 24 San Diego State Aztecs

Spread Prediction

• Computer Prediction: San Diego State 81, Fresno State 64
• Projected Favorite: San Diego State by 16.5 points
• Pick ATS: San Diego State (-14.5)

Bet on the Fresno State-San Diego State spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

• Time: 10:30 PM ET
• Location: Fresno, California
• Venue: Save Mart Center
• TV Channel: Fox Sports 1
• Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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